United States securities and exchange commission logo

                     June 10, 2022

       Billy Cho
       Chief Financial Officer
       Zai Lab, Ltd.
       4560 Jinke Road
       Bldg. 1, Fourth Floor
       Shanghai, China

                                                        Re: Zai Lab, Ltd.
                                                            Form 10-K for
Fiscal Year Ended December 31, 2020
                                                            Filed March 1, 2021
                                                            File No. 001-38205

       Dear Mr. Cho:

              We have completed our review of your filing. We remind you that
the company and its
       management are responsible for the accuracy and adequacy of their
disclosures, notwithstanding
       any review, comments, action or absence of action by the staff.


                     Division of Corporation Finance

                     Office of Life Sciences
       cc:                                              Thomas Danielski