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                       October 30, 2020

       Billy Cho
       Chief Financial Officer
       Zai Lab Ltd
       4560 Jinke Road
       Bldg. 1, Fourth Floor
       Pudong
       Shanghai, China 201210

                                                        Re: Zai Lab Ltd
                                                            Form 20-F for the
fiscal year ended December 31, 2019
                                                            Filed April 29,
2020
                                                            File No. 001-38205

       Dear Mr. Cho:

              We have completed our review of your filing. We remind you that
the company and its
       management are responsible for the accuracy and adequacy of their
disclosures, notwithstanding
       any review, comments, action or absence of action by the staff.




                       Sincerely,


                       Division of Corporation Finance

                       Office of Life Sciences